Prof. Aparna Dixit
 

Dr. Aparna Dixit
Professor
Ph: +91 11 26704085 ; +91 11 26742533
Email: adix2100@mail.jnu.ac.in ; adixit7@yahoo.com

Education

Ph. D. (Life Sciecnes), Jawaharlal Nehru University, New Delhi
M.Sc. (Biochemistry), Allahabad University, Allahabad

Career:

2004-
Professor, School of Biotechnology, JNU, New Delhi.
1996-2004
Associate Professor, Special Centre for Biotechnology, JNU, New Delhi.
2003(April- Sept.)
Visiting Scientist, Department of Biochemistry, Kansas State University, Manhattan, KS, USA
1992-1996
Assistant Professor, Dept. of Zoology, University of Delhi, Delhi
1991-1992
Scientist, Centre for Plant Molecular Biology, SLS, JNU, New Delhi
1990-1991
CSIR Pool Officer, SLS, JNU, New Delhi
1985-1989
Instructor and Res. Associate, Department of Pharmacology, The Milton S. Hershey Medical Center, The Pennsylvania State University, Hershey, PA, USA.
1983-1985
Research Associate, Division of Biology, Kansas State University, Manhattan,   KS, USA
1981-1983
Research Associate, Division of Biology, Kansas State University, Manhattan, KS, USA.

Research Interest:

  • Transcriptional regulation of oncogenes and signal transduction in relation to proliferation and cancer
  • Identification of bioactive principles from natural sources for the treatment of diabetes, leukemia and microbial infections; and their mechanisms of action
  • Development of recombinant and DNA vaccines against bacteria of Aeromonas spp.

Honors/Awards:

  • National Merit Scholarship for postgraduate studies
  • DBT Overseas Associateship Award 2001-2002  for 6 months

Selected Publications:

  1. S. Agarwal, R. Kumar, P. Gupta and A. Dixit (2008). Identification and characterization of a positive regulatory cis-element within the upstream region of c-jun.  J. Biochem., 144: 741-752.
  2. V. Sharma, P. Gupta and A. Dixit (2008). In silico identification of putative drug targets from different metabolic pathways of Aeromonas hydrophila.  In silico Biol., 8: 331-338.
  3. S. Agarwal, K. Gopal, T. Upadhyaya and A. Dixit (2007). Biochemical and functional characterization of UDP-galactose 4-epimerase from Aeromonas hydrophila.  Biochim. Biophys. Acta - Proteins and Proteomics,  1774: 828-837.
  4. A. Vashishta, T. Sahu, A. Sharma, S. K. Choudhary and A.Dixit (2006). In vitro refolded napin-like protein of Momordica charantia expressed in Escerichia coli displays properties of native napin. Biochim.  Biophys. Acta- Proteins and Proteomics, 1764: 847-855.
  5. S. Ohri, D. Sharma and A. Dixit (2004). Interaction of a ~40 kDa protein from regenerating rat liver with the -148 to -124 region of c-jun complexed with the RLjunRP coincides with enhanced c-jun expression in proliferating rat liver. Eur. J. Biochem., 271: 4892-4902.
  6. D. Sharma, S. Ohri and A. Dixit (2003). –148 to –124 region of c-jun  gene interacts with positive regulatory factor in rat liver  and enhances transcription. Eur. J. Biochem., 270: 181-189.
  7. D. Sharma, S. K. Choudhary and A. Dixit (1998). In vitro transcription of c‑jun gene using nuclear extracts of regenerating rat liver. Biochem. Mol. Biol. Int., 44: 1175-1185.
  8. A. Dixit, L. C. Garg and S.T. Jacob (1989). A Cis‑Acting sequence within the rat ribosomal DNA enhancer region can modulate RNA Polymerase II ‑directed transcription of the metallothionein‑I gene in vitro. DNA, 8: 311‑320.
  9. A. Dixit, L. C. Garg, W. Chao and S. T. Jacob (1987). An enhancer element in the far upstream spacer region of rat ribosomal RNA gene. J. Biol. Chem., 262: 11616‑11622.
  10. I. Tsuen Chen, A. Dixit, D.D. Rhoads and D.J. Roufa (1986). Homologous ribosomal proteins in bacteria, yeast and man. Proc. Natl. Acad. Sci. USA., 83: 6907‑6911.
  11. D. D. Rhoads, A. Dixit and D. J. Roufa (1986). Primary structure of human ribosomal protein S14 and the gene that encodes it. Mol. Cell. Biol., 6: 2774‑2783.
  12. A. Dixit and T. E. Roche (1984). Spectrometric assay of the flavin containing monooxygenase and changes in its activity in female mouse liver with nutritional and diurnal conditions. Arch. Biochem. Biophys., 233: 50‑63.

 

 

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