Sneh Lata Panwar
Assistant Professor
School of
Life Sciences
Jawaharlal Nehru University
New Delhi -110067, India.
Room No. : 203
Off. Phone : 26704620 
E-mail : ,


Ph.D (1996-2001): School of Life Sciences, Jawaharlal Nehru University, New Delhi (Yeast Molecular Genetics).


2006 August-to date

Assistant Professor, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067.

2005 Nov-2006 Aug

Research Associate, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110067.


Postdoctoral Fellow, University of Iowa, Iowa City, USA


Postdoctoral Fellow, University of Minnesota, Twin Cities Campus, Minneapolis, USA

Area of Research

Yeast Molecular Genetics with a special focus on the various mechanisms of Multi drug resistance (MDR) in the pathogenic fungus Candida albicans. These studies include looking into the role of membrane homeostasis as a determinant of drug resistance in C. albicans. The other part of our research focuses on retrograde regulation of drug resistance, which includes analyzing the role of mitochondria in drug resistance in this pathogenic yeast. Transcription regulation of the various genes involved in drug resistance is also analyzed in our laboratory.

Awards and Honour

Innovative Young Biotechnologist Award for 2007 (IYBA-2007) by Department of Biotechnology, Ministry of Science and Technology, Govt of India.

Awarded C. R. Krishnamurthy Young Scientist Award in 2000.

Delhi University Gold Medal for standing first in M. Sc Biochemistry, South campus, New Delhi in 1994

1994. Qualified the JRF/NET Fellowship awarded by the Council for Scientific and Industrial Research, Government of India.

1994. Qualified the Graduate Aptitude Test in Engineering (percentile score 99.14). All India Rank- 20


1.      American Society for Microbiology

Selected Publications


Pasrija, R., Panwar, SL and Prasad, R. (2008). Multidrug transporters CaCdr1p and CaMdr1p of Candida albicans display different lipid specificities: both ergosterol and sphingolipids are essential for targeting of CaCdr1p to membrane rafts. Antimicrob Agents Chemother; 52:694-704.

Manoharlal R, Gaur NA, Panwar SL, Morschhäuser J, Prasad R. (2008). Transcriptional activation and increased mRNA stability contribute to overexpression of CDR1 in azole-resistant Candida albicans. Antimicrob Agents Chemother. 52:1481-92.

Panwar, SL and Moye-Rowley WS. Long chain base tolerance in Saccharomyces cerevisiae in induced by retrograde signals from the mitochondria (2006).  J. Biol. Chem. 281: 6376-6384.

Zhang, X., Kolackowzsi, A., Deveaux, F., Panwar, SL., Hallstrom TC., Jacq C. and Moye-Rowley WS (2005). Transcriptional  regulation by Lge1p requires a function independent of its role in histone H2B ubiquitination. J. Biol. Chem. 280 : 2759-2770.

Panwar, SL., Legrand, M., Dignard D., Whiteway, M. and Magee, P. T. (2003). Identification and characterization of the gene encoding the a mating pheromone of Candida albicans. Eukaryotic Cell. 2: 1350-1360.

Panwar, SL., Krishnamurthy, S., Gupta, V., Alarco, A.–M., Raymond, M., Sanglard, D. and Prasad, R (2001). CaALK8, an alkane assimilating cytochrome P450 confers multidrug resistance when expressed in a hypersensitive strain of Candida albicans. Yeast 18:1117-1129.

Krishnamurthy, S., Gupta, V., Panwar, SL and Prasad, R (1998). Characterisation of human steroid hormone efflux mediated by Cdr1p, a multidrug transporter of Candida albicans, belonging to ABC super family. FEMS Microbiol. Letts. 158 (1) 69-74.

Krishnamurthy, S., Chatterjee, U. Gupta, V., Prasad, R., Das, P., Panwar, SL., Hasnain, S. E. and Prasad, R. (1998). Deletion of transmembrane domain (TM) 12 of CDR1 a multidrug transporter from Candida albicans, leads to altered drug specificity: Expression of a yeast multidrug transporter in Baculovirus expression system. Yeast 14, 535-550.

Krishnamurthy, S., Gupta, V., Panwar, SL and Prasad, R (1998). Expression of CDR1, multidrug resistance gene of Candida albicans: in vitro transcriptional activation by heat shock, drugs and human steroid hormones. FEMS Microbiol. Letts. 160, 191-197.

Gupta, V., Kohli, A., Krishnamurthy, S., Puri, N., Aalamgeer, S. A., Panwar, S. and Prasad, R. (1998). Identification of polymorphic mutant alleles of CaMDR1, a major facilitator of Candida albicans which confers multidrug resistance and its in vitro transcriptional activation. Curr. Genet. 34: 192-199.


R. Prasad and Sneh Lata Panwar (2003) Physiological relevance of multidrug transporters in yeasts. Current Science

R. Prasad and Sneh Lata Panwar and Smriti (2001) Drug resistance in yeasts- An emerging scenario. Adv Microb. Physiol. 46; 156-189.

R. Prasad., S. KrishnaMurthy, V. Gupta and Sneh Lata Panwar (1998) Multidrug transporters of Candida albicans. Folia Microbiol. 43, 228.

R. Prasad, S. KrishnaMurthy, Ramasare Prasad, Vinita Gupta and Sneh Lata Panwar.  (1996) Multidrug resistance: an emerging threat. Curr. Sci. 71, 205-213.

Book Chapters

R. Prasad, Sneh Lata Panwar and S. Krishnamurthy. Drug Resistance Mechanisms of Human Pathogenic Fungi. In: Fungal Pathogenesis: Principles and Clinical Applications., R. Cihlar and R. A. Calderone, (Eds).Marcel Dekker (2001).

R. Prasad, Sneh Lata Panwar and Neeti Puri. Sex and Drug ATPases in Yeasts. In: Biophysical Processes in Living systems., P. Pardha Saradhi Ed. Oxford and IBH Publishing Co. Pvt. Ltd. (2001).

Projects undertaken

Sponsoring Agency: Department of Science and Technology
Membrane homeostasis: An important determinant of drug susceptibilities in the human pathogenic fungus Candida albicans
Duration:  2007 - 2010

Sponsoring Agency: Department of BioTechnology
Title: Role of Mitochondria in multidrug resistance in Candida albicans
Duration:  2008 - 2011