* Molecular Biology of Infectious Diseases
* Recombinant Vaccine Development
* Programmed cell death in prokaryotes |
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Experience |
(a) Administrative Experience
2011 onwards: Director, Academic Staff College, Jawaharlal Nehru University, New Delhi.
2009-2011: Director, Advanced Instrumentation Research Facility, Jawaharlal Nehru University, New Delhi.
2006 onwards : Chairman, Intellectual Property Management Cell, Jawaharlal Nehru University, New Delhi.
2001 - 2003 : Chairman, Centre for Biotechnology, Jawaharlal Nehru University, New Delhi.
1993 - 1995 : Chairman, Centre for Biotechnology, Jawaharlal Nehru University, New Delhi.
1990 - 1993 : Chairman, Bioinformatics Centre, Jawaharlal Nehru University, New Delhi.
(b) Academic Experience
1997 onwards : Professor, School of Biotechnology, Jawaharlal Nehru University, New Delhi.
1989 - 1997 : Associate Professor, Centre for Biotechnology, Jawaharlal Nehru University, New Delhi.
1987 - 1989 : Senior NRC Associate, USAMRIID, Fredrick MD, USA.
1986 - 1987 : Visiting Associate, NHLBI, NIH,Bethesda, MD, USA.
1985 - 1986 : Visiting Assistant Prof., Lab. Connective Tissue, Biochemistry, CHU, Caen, FRANCE.
1983 - 1985 : Assistant Professor of Biochemistry, Post Graduate Institute of Med. Education & Research, Chandigarh.
1982 - 1983 : Pool Officer, Department of Biochemistry, V. P. Chest Institute, University of Delhi.
1979 - 1982 : Scientist (Wiessenschaftliecher Angeschtelter), Institute of Biochemistry and Molecular Biology, Freiburg University, Freiburg, GERMANY. |
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Awards & Honours |
* Prof. Rakesh Bhatnagar was ranked among the top 10(Actually 7 from top) eminent researchers publishing commendable research papers on anthrax. (Open source Global Anthrax Research Literature 2006)
* Fellow, National Academy of Sciences, India.
* Fellow, Indian Academy of Sciences, India.
* Indian Council of Medical Research (ICMR) award for outstanding research work in the field of Immunology (Development of recombinant anthrax vaccine) for the year 2001, received on 14th Dec. 2003.
* All India Biotech Association Award 2001-2002, in recognition of achievements in Promotion of Biotechnology, In the Area of Biotechnology for Health Care. |
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International Collaboration/Consultancy |
* Prof. Vitor Martin dos Santos, Systems and Synthetic Biology, Wageningen University, Netherlands.
* Associate Professor Ram Samudral, Computational Biology Research Group University of Washington, Seattle.
* Prof. Venugopal Nair, Head, Avian Infectious Disease, Institute of Animal Health, Biotechnology and Biological Sciences Research Council. United Kingdom |
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Best Peer Reviewed Publications (upto 5) |
1. Kulshrestha P. and Bhatnagar R.(2011). Inhibition of anthrax toxins with a bispecific monoclonal antibody that cross reacts with edema factor as well as lethal factor of Bacillus anthracis. Molecular Immunology 48:1958-65.
2. Gorantala J, Grover S, Goel D, Rahi A, Chandra S, Bhatnagar R (2011). A plant based protective antigen [PA(dIV)] vaccineexpressed in chloroplasts demonstrates protective immunity in mice against anthrax. Vaccine29:4521-33.
3. Kaur M., Saxena A., Rai A. and Bhatnagar R. (2010) Rabies DNA vaccine encoding lysosome targeted glycoprotein supplemented with EMULSIGEN D confers complete protection in pre-and post-exposure studies in BALB/c mice. FASEB J 24, 173-183.
4. Agarwal S., Mishra N.K., Bhatnagar S. and Bhatnagar R. (2010) PemK Toxin of Bacillus anthracis Is a Ribonuclease an insight into its active site,structure,and function .J.Biol.Chem 285,7254-7270.
5. Midha S. and Bhatnagar R. (2009) Anthrax protective antigen administered by DNA vaccination to distinct subcellular locations potentiates humoral and cellular immune responses. European Journal of Immunology 39(1): 159- 177. |
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Recent Peer Reviewed Journals/Books (upto 3) |
1. Gorantala J, Grover S, Goel D, Rahi A, Chandra S, Bhatnagar R (2011). A plant based protective antigen [PA(dIV)] vaccineexpressed in chloroplasts demonstrates protective immunity in mice against anthrax. Vaccine29:4521-33.
2. Nikita Chopra, Shivangi Agarwal, Shashikala Verma, Sonika Bhatnagar and Rakesh Bhatnagar “(2011). Modeling of the structure and interactions of the B. anthracis antitoxin, MoxX: deletion mutant studies highlight its modular structure and repressor function. J Comput Aided Mol Des 25:275–291.
3. Rahi A., Rehan M., Garg R, Tripathi D., Lynn A.M., and Bhatnagar R. (2011). Enzymatic characterization of Catalase from Bacillus anthracis and prediction of critical residues using information theoretic measure of Relative Entropy. Biochem. Biophys. Res. Commun 411(1):88-95. |
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Patents (if any) |
* R. Bhatnagar (2010) A novel bispecific monoclonal antibody capable of cross reacting with the lethal factor(LF) and edema factor(EF) and neutralizing edema toxin(ET) as well as lethal toxin(LT) of Bacillus anthracis. Indian patent (714/DEL/2010) application filed.
* R. Bhatnagar (2008) A Pharmaceutical Composition of Vaccine against Rabies which Comprises of DNA Vaccine based on Glycoprotein Gene of Rabies Virus Conjugated to LAMP-1 Signal Sequence of the C-Terminus and an Adjuvant and Method of its Preparation thereof . Indian patent (1449/DEL/2008) application filed.
* R. Bhatnagar (2007, 2008). DNA vaccine against Anthrax. Indian patent (2355/DEL/2007) and International PCT (PCT/IN2008/000761) applications filed.
* R. Bhatnagar (2007, 2008). Insecticidal XnGroEL protein from Xenorhabdus nematophila Indian Patent (1092/DEL/2007) and International PCT (PCT/IN2008/000316) application filed.
* R. Bhatnagar (2005). Transformation of an edible crop with paga Gene of Bacillus Anthracis. Indian patent (2078/DEL/2005) application filed.
* R. Bhatnagar (2002).An Anthrax Protective Antigen. Indian patent (1074/Del/2002) application filed.
* R. Bhatnagar (2001-2002). A Process for the Preparation of Non-Toxic Anthrax Vaccine. Indian patent (1222/Del/2001) accepted. International PCT application (PCT/IN2002/00048; WO-03-048390A1, June 12, 2003) published.
* R. Bhatnagar (2001). A process for constitutively preparing anthrax protective antigen. Indian patent (1127/Del/2001) accepted.
* R. Bhatnagar (2001). An Anthrax Protective Antigen. Indian patent (1074/Del/2002) accepted.
* R. Bhatnagar (2001). High Level Constitutive Production of Anthrax Protective Antigen. International PCT application (PCT/IN01/00215; WO-03-040179A1, 15 May 2003) published. |
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