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Research Projects

 


Completed Projects

  1. Prasad. R, Mukhopadhyay, G. & Banerjee U. (AIIMS). Molecular biotyping, epidemiology and fungal susceptibilities of opportunistic human pathogenic fungi, ICMR, (2002-2005).
  2. Dhar, S.K. Functional characterization of replication origin (oric) & replication proteins of Helicobacter pylori. CSIR, (2002-2005).
  3. Dhar S.K. Functional characterization of replication proteins & replication origin (oric) of Helicobacter pylori: potential targets for therapy, University Potential of Excellence Scheme, JNU, (2002-2007).
  4. Tyagi R.K. Investigation into androgen-independent activation of androgen receptor in prostate cancer. ICMR, (2003-2006).
  5. Mukhopadhyay C.K. A Study on the molecular mechanism of insulin-induced activation of hypoxia-inducible factor-1, the master regulator of oxygen homeostasis. DBT, (2003-2006).
  6. Tyagi R.K. Mechanisms of inhibition of transcriptional activity of androgen receptor by antagonists/endocrine disruptors CSIR, (2003-2006).
  7. Mukhopadhyay G. Biochemical analysis of the type IV protein secretion system of Helicobacter pylori” CSIR, (2003-2006).
  8. Mukhopadhyay G. Prasad R. Data A. Molecular aspects of candidiasis collaborated with Prof. Rajendra Prasad, SCMM & SLS. DBT, (2003-2006).
  9. Tyagi R.K. Role of pregnanae X receptor (PXR) in lung cancer. Bangalore Science Foundation, (2004-2006).
  10. Mukhopadhyay C.K. A study on the plausible molecular mechanism(s) on hepatic iron overload in hyperinsulinemia. CSIR, (2004-2007).
  11. Dhar S. K. Functional analysis of replication and cell cycle regulated genes in Plasmodium falciparum The Wellcome Trust, UK (2003-08).
  12. Mukhopadhyay G. in collaboration with Prof. Rajendra Prasad, SCMM, & Asis Datta SLS. Molecular aspects of morphogenesis & antifungal resistance in human fungal pathogens in Candida albicans. DBT, (2007-2010).
  13. Dhar S.K. in collaboration with Dr. Santanu Dasgupta, Upsala University, Sweden. DNA replication restart mechanism in Helicobacter Pylori. Indo-Swedish Link grant (2007-09)
  14. Mukhopadhyay G. “Analysis of the structural features of the Helicobacter pylori Type IV secretion system and its interactions with host cell”. Council of Scientific & Industrial Research (2006-09).
  15. Mukhopadhyay CK. Investigation on regulation of transferrin receptor by insulin. Indian Council of Medical Research (2007-09).
  16. Tyagi RK, Modulatory effects of herbal drug ingredient(s) on transcription factor Pregnane & Xenobiotic Receptor (PXR): Evaluation for therapeutic potency and health safety assessment. Department of Science & Technology. (2006-09). (Extended till 30.08.10).
  17. Tyagi RK. “Interrogating the role of a novel xenosensor ‘Steroid and Xenobiotic Receptor’ in metabolism and elimination of endocrine disruptors and pesticides.” Council of Scientific & Industrial Research (2006-09). (Extended to fourth year till July 2010).
  18. Mukhopadhyay CK. Role of iron in growth of Leishmania donovani and in interaction with macrophage. The Wellcome Trust, London, UK (2005-11) Continuation of The Wellcome Trust International Senior Research Fellowship.

PROJECTS IN PROGRESS

  1. Dhar SK. “Control of DNA replication initiation and cell cycle regulation in two important human pathogens: Plasmodium falciparum and Helicobacter pylori” by the Department of Science and Technology (DST) under its “Swarnajayanti Fellowship” scheme in Biological Sciences. (2009-14)
  2. Dhar SK. “Signalling in Malaria Parasites: MALSIG”. The European Com mission, (2009-12).
  3. Dhar SK. “Programme Support on Molecular Parasitology” to work on the project entitled “Characterization of DNA replication and non-replication function of two putative homologues of Plasmodium falciparum Origin Recognition Complex” Department of Biotechnology (DBT) (2011-2016).
  4. Dhar SK. National Biosciences Award to work on project entitled “Functional characterization of unique bacterial gyrase in the malaria parasite Plasmodium falciparum with codon optimization and screening some novel gyrase inhitors” Department of Biotechnology (DBT) (2011-2014).
  5. Aijaz S. “A study on the mechanisms of paracellular permeability by the tight junction protein, occludin”. Department of Biotechnology (DBT), (2009-12).
  6. Tyagi RK. “Studies to decipher the functional implications of nuclear receptors docking onto the mitotic chromatin” Council of Scientific and Industrial Research (CSIR), (2010-13).
  7. Mukhopadhyay CK. “Studies on regulation of mammalian iron transporter transferrin receptor by catecholamines”. Council of Scientific and Industrial Research (CSIR), (2011-2013).
  8. Mukhopadhyay CK. Studies on the mechanism of activation of hypoxia-inducible factor-1 in Leishmania donovani infected macrophages and its role on intracellular growth of the parasite (2011-2013).
  9. Mukhopadhyay CK. “Programme Support on Molecular Parasitology” to work on the project entitled “Studies on molecular mechanisms by which intracellular Leishmania donovani subverts iron pool of host macrophage for its survival advantage” (2011-2015).
  10. Mukhopadhyay CK. “"Role of Brain Ferroxidases in AD and sCJD Pathogenesis" in U.S.-India Bilateral Brain Research Collaborative Partnerships (U.S. – India BRCP) (R21) (2012-2013).
  11. Tyagi RK Generation of monoclonal antibodies against a nuclear receptor ‘Pregnane & Xenobiotic Receptor’ for utility as immunological and diagnostic tool. 2012-2015 University Grants Commission (UGC).
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