Latest Publications

  1. Pawar H, Puri M, Fischer Weinberger R, Madhubala R, Zilberstein D. The arginine sensing and transport binding sites are distinct in the human pathogen Leishmania. PLoS Negl Trop Dis. 2019 Apr 24;13(4):e0007304. doi: 10.1371/journal.pntd.0007304. eCollection 2019
  2. Bansal R, Sen SS, Muthuswami R, Madhubala R. A Plant like Cytochrome P450 Subfamily CYP710C1 Gene in Leishmania donovani Encodes Sterol C-22 Desaturase and its Over-expression Leads to Resistance to Amphotericin B. PLoS Negl Trop Dis. 2019 Apr 3;13(4):e0007260. doi: 10.1371/journal.pntd.0007260. eCollection 2019
  3. Manhas R, Tandon S, Sen SS, Tiwari N, Munde M, Madhubala R. Leishmania parasites are inhibited by the benzoxaborole AN2690 targeting leucyl-tRNA synthetase Antimicrob Agents Chemother. Jun 25. pii: AAC.00079-18. doi: 10.1128/AAC.00079-18. [Epub ahead of print] 2018
  4. Chadha S, Vijayan R, Gupta S, Munde M, Gourinath S, Madhubala R. Genetic manipulation of Leishmania donovani threonyl tRNA synthetase facilitates its exploration as a potential therapeutic target. PLoS Negl Trop Dis. Jun 13;12 (6):e0006575. doi: 10.1371/journal.pntd.0006575. [Epub ahead of print] 2018
  5. Sanya Chadha, N. Arjunreddy Mallampudi, Debendra K. Mohapatra, and Rentala Madhubala. Genetic Validation of Leishmania donovani Lysyl-tRNA Synthetase shows that It Is Indispensable for Parasite Growth and Infectivity mSphere, Aug 30; 2 (4). pii: e00340-17. doi: 10.1128/mSphereDirect.00340-17. eCollection 2017
  6. Nimisha Mittal, Rohini Muthuswami and Rentala Madhubala The mitochondrial SIR2 related protein 2 (SIR2RP2) impacts Leishmania donovani growth and infectivity pLOS Neglected Tropical Diseases. 11;11(5): e0005590. doi: 10.1371/journal.pntd.0005590, 2017
  7. Ruby Bansal, Himanshu Bhusan Samal, V S Gowri, Shib Sankar Sen, Indira Ghosh and Rentala Madhubala The Cytochrome P450 Complement (CYPome) of Leishmania leads to the discovery of a plant like Cytochrome P450 subfamily CYP710C1 gene. Proceedings of Indain National Science Academy, PINSA, DOI: 10.16943/ptinsa/2017/49026, 2017