Rohini Muthuswami | Welcome to Jawaharlal Nehru University

Rohini Muthuswami

Professor

Centre/School/Special Centre

School of Life Sciences

Room No

333

Off. Phone

011-26704154

Residence

011-26742151

rohini_m@mail.jnu.ac.in

Personal Webpage

https://sites.google.com/view/profrohinimuthuswami

Qualifications

B.Sc (Chemistry) Hindu College, Delhi University
M.Sc (Biotechnology) M.S. University, Baroda
Ph.D. (Biochemistry) University of Virginia

Areas of Interest/Specialization

Epigenetics and Chromatin remodeling

Experience

Associate Professor, School of Life Sciences, JNU 2014- present
Assistant Professor, School of Life Sciences, JNU, 2004-2014
Science fellow, Aurigene Discoveries Pvt. Ltd. 2002-2004
Post-doctoral fellow, University of Colorado Health Sciences Center, 1998-2002

Awards & Honours

* UICC Yamagiwa-Yoshida Memorial International Study Grant, 2009.
* BF Goodrich Collegiate Inventors Prize, 1998 http://www.invent.org/collegiate/winners.html
* President’s Fellowship, University of Virginia, 1993-1996
* Junior Research Fellowship, University Grants Commission, India, 1991-1993
* Department of Biotechnology Scholarship, India, 1991-1993
* Professor Suri Award, Delhi University, 1989
* Professor Seshadri Prize, Delhi University, 1989
* First position in Chemistry, B.Sc. (Honours) Examination, Delhi University, 1989

International Collaboration/Consultancy

None

Best Peer Reviewed Publications

1. Haokip, D.T., Goel, I., Arya, V., Sharma, T., Kumari, R., Priya, R., Singh, M., and Muthuswami, R., Transcriptional regulation of ATP-dependent chromatin remodeling factors: SMARCAL1 and BRG1 mutually co-regulate each other. (2016). Scientific Reports (Manuscript accepted for publication).
2. Sharma, T., Bansal, R., Haokip, D.T., and Muthuswami, R., SMARCAL1 negatively regulates c-myc transcription by altering the conformation of the promoter region (2015). Scientific Reports 5:17910.
3. Gupta, M., Mazumdar, M., Datchinamoorthy, K., Gourinath, S., Nongkhlaw, M., Komath, S.S., and Muthuswami, R., Ligand induced conformational changes drive ATP hydrolysis in SMARCAL1 (2015). FEBS J. 282: 3841-3859.
4. Dutta, P., Tanti, G.K, Sharma, S., Goswami, S.K., Komath, S.S., Mayo, M.W., Hockensmith, J.W., and Muthuswami, R., Global epigenetic changes induced by SWI2/SNF2 inhibitors characterize neomycin resistant mammalian cells. (2012), PLoS One. 7(11): e49822.
5. Nongkhlaw, M., Gupta, M., Komath, S.S., and Muthuswami, R. Motifs Q and I are required for ATP hydrolysis but not for ATP binding in SWI2/SNF2 proteins. (2012) Biochemistry, 51: 3711-22.

Patents (if any)

* Muthuswami, R., and Hockensmith, J.W., Methods and Compositions for Targeting DNA Metabolic Processes Using Aminoglycoside Derivatives. U.S. Patent Number: 6,180,612.
* Muthuswami, R., and Hockensmith, J.W., Methods and Compositions for Targeting DNA Metabolic Processes Using Aminoglycoside Derivatives US patent number 6,573,060
* Muthuswami, R., and Hockensmith, J.W., Mammalian DNA-dependent ATPase a polypeptides and fusions thereof US patent number 6,573,791
* Muthuswami, R., and Hockensmith, J.W., Polynucleotides encoding mammalian DNA-dependent ATPase A polypeptides US patent number 6,573,306