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Stanzin Dawa

Stanzin Dawa
Stanzin Dawa
Assistant Professor
Centre/School/Special Centre
School of Life Sciences
Room No
433
Email
stanzin[at]mail[dot]jnu[dot]ac[dot]in
Personal Webpage
https://jnu.ac.in
Qualifications

Ph.D. Biological Sciences, 2022, CSIR-Institute of Genomics and Integrative Biology, (IGIB) New Delhi, India.
M.Sc. Biotechnology, 2014, University of Jammu
B.Sc. Life Sciences, 2012, University of Jammu

Areas of Interest/Specialization

Tuberculosis, Immunology, Infectious Diseases, Pulmonary Tuberculosis Histopathology

Our lab is interested in deciphering the early immune drivers in the host lung during Mycobacterium tuberculosis infection that lays the ground for a bacterial growth permissive micro-environment in the lung. Focusing on the early recruitment of myeloid lineage immune cells in the lung and the development of structurally multilayered myeloid rings in the TB granulomas with distinct functional outcome after M. tuberculosis infection. Our goal is to unravel the host molecular defector during early stage of the infection and devise an effective early intervention strategy.

Experience

Assistant Professor (Immunology)- School of Life Sciences, JNU, May 2025- Present
Post-doctoral Scientist- Emory University, Atlanta, Georgia, USA - 2022-2025

Awards & Honours

Keystone Symposia (Tuberculosis) Scholarship Feb 2025, Boston, USA
JRF/SRF from Department of Biotechnology, Govt. of India.

International Collaboration/Consultancy

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Best Peer Reviewed Publications

  1. Dawa S, Menon D, Arumugam P, Bhaskar AK, Mondal M, Rao V, Gandotra S. Inhibition of Granuloma Triglyceride Synthesis Imparts Control of Mycobacterium tuberculosis Through Curtailed Inflammatory Responses. Front Immunol. 2021 Sep 15; 12:722735. https://doi:10.3389/fimmu.2021.722735. PMID: 34603294; PMCID: PMC8479166.

  2. Jaisinghani N, Dawa S, Singh K, Nandy A, Menon D, Bhandari PD, Khare G, Tyagi A, Gandotra S. Necrosis Driven Triglyceride Synthesis Primes Macrophages for Inflammation During Mycobacterium tuberculosis Infection. Frontiers in Immunology, 9, 01490, (2018), https://doi.org/10.3389/fimmu.2018.01490.

  3. Shankaran D, Singh A, Dawa S, Arumugam P, Gandotra S, Rao V. The antidepressant sertraline provides a novel host directed therapy module for augmenting TB therapy. Elife. 2023 Jan 11;12: e64834. PMID: 36629405; PMCID: PMC10159622. https://doi.org/10.7554/eLife.64834 

  4. Nandy A, Mondal AK, Pandey R, Arumugam P, Dawa S, Jaisinghani N, Rao V, Dash D, Gandotra S. Adipocyte Model of Mycobacterium tuberculosis Infection Reveals Differential Availability of Iron to Bacilli in the Lipid-Rich Caseous Environment. Infect Immun. 2018 May 22;86(6): e00041-18. https://doi.org/10.1128/iai.00041-18 PMID: 29632245; PMCID: PMC5964510. 

  5. Kgoadi K, Bajpai P, Ibegbu CC, Dkhar HK, Enriquez AB, Dawa S, Cribbs SK, Rengarajan J. Alveolar macrophages from persons with HIV mount impaired TNF signaling networks to M. tuberculosis infection. Nat Commun. 2025 Mar 10;16(1):2397. PMID: 40064940; PMCID: PMC11894076. https://doi.org/10.1038/s41467-025-57668-y  

Recent Peer Reviewed Journals/Books

  1. Kgoadi K, Bajpai P, Ibegbu CC, Dkhar HK, Enriquez AB, Dawa S, Cribbs SK, Rengarajan J. Alveolar macrophages from persons with HIV mount impaired TNF signaling networks to M. tuberculosis infection. Nat Commun. 2025 Mar 10;16(1):2397. PMID: 40064940; PMCID: PMC11894076. https://doi.org/10.1038/s41467-025-57668-y 

  2. Shankaran D, Singh A, Dawa S, Arumugam P, Gandotra S, Rao V. The antidepressant sertraline provides a novel host directed therapy module for augmenting TB therapy. Elife. 2023 Jan 11;12: e64834. PMID: 36629405; PMCID: PMC10159622. https://doi.org/10.7554/eLife.64834 

  3. Dawa S, Menon D, Arumugam P, Bhaskar AK, Mondal M, Rao V, Gandotra S. Inhibition of Granuloma Triglyceride Synthesis Imparts Control of Mycobacterium tuberculosis Through Curtailed Inflammatory Responses. Front Immunol. 2021 Sep 15; 12:722735. https://doi: 10.3389/fimmu.2021.722735. PMID: 34603294; PMCID: PMC8479166.

  4. Jaisinghani N, Dawa S, Singh K, Nandy A, Menon D, Bhandari PD, Khare G, Tyagi A, Gandotra S. Necrosis Driven Triglyceride Synthesis Primes Macrophages for Inflammation During Mycobacterium tuberculosis Infection. Frontiers in Immunology, 9, 01490, (2018), https://doi.org/10.3389/fimmu.2018.01490 .

  5. Nandy A, Mondal AK, Pandey R, Arumugam P, Dawa S, Jaisinghani N, Rao V, Dash D, Gandotra S. Adipocyte Model of Mycobacterium tuberculosis Infection Reveals Differential Availability of Iron to Bacilli in the Lipid-Rich Caseous Environment. Infect Immun. 2018 May 22;86(6): e00041-18. https://doi.org/10.1128/iai.00041-18 PMID: 29632245; PMCID: PMC5964510. 

Patents (if any)

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