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Ajay Kumar Saxena

Ajay Kumar Saxena
Ajay Kumar Saxena
Professor
Centre/School/Special Centre
School of Life Sciences
Room No
403
Off. Phone
011-26704155
Email
ajaysaxena[at]mail[dot]jnu[dot]ac[dot]in
Personal Webpage
https://jnu.ac.in/Faculty/asaxena/cv.pdf
Qualifications

Ph.D. in Protein Crystallography 

Areas of Interest/Specialization

Structural Biology on Disease related proteins, Structure guided Drug/Vaccine development 

Experience
03/2011- Present Professor, Structural Biology Section, Jawaharlal Nehru University, India.

2005-2011 Associate Professor, Structural Biology Section, Jawaharlal Nehru University, India.

1998-2005 Research Fellow, Structural Biology Section, NIAID, National Institutes of Health, USA.

1996-1998 Postdoctoral Fellow, Institute of Biophysics & X-ray Structure Research, Austrian Academy of Sciences, Austria, Europe  
Awards & Honours
  1. NPG group, Bill & Melinda gates foundation travel award to attend GRC
  2. John E. Fogatry International Fellowship, NIH, USA
  3. Austrian Academy of Science Fellowship, OAW, Austria, Europe
  4. Senior Research Fellowship, DBT, India 
International Collaboration/Consultancy
  1. Dr. Shiv Srivastava, Scientific Director, CPDR, USUHS, USA
  2. Dr. David N. Garboczi, NIAID, NIH, USA 
Best Peer Reviewed Publications
  1. Arkita Bandhopadhyay and Ajay K. Saxena# (2021). Structural and ATPase activity analysis of nucleotide binding domain of Rv3870 enzyme of M. tuberculosis ESX-1 system.

    Int. J. Biol. Macromol 189: 879–889.
  2. Sumita Karan, Ankita Behl, Amin Sagar, Arkita Bandhopadhyay and Ajay K. Saxena# (2021). Structural studies on Mycobacterium tuberculosis HddA enzyme using small angle X-ray scattering and dynamics simulation techniques,

    Int. J. Biol. Macromol.171:28-36.
  3. S. Karan, B. Pratap, Shiv P. Yadav, FNU. Ashish & Ajay K. Saxena# (2020). Structural and functional characterization of M. tuberculosis sedoheptulose‑7‑phosphate isomerase, a critical enzyme involved in lipopolysaccharide biosynthetic pathway.

    Nature Sci. Rep. 10(1):20813.
  4. Manford, T. Xia, A. K. Saxena, C. Stefan, F. Hu, S. D. Emr and Y. Mao (2010). Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function (PDB-3LWT).

    EMBO J. 29(9), 1489-1498.
  5. Saxena, A. K.#, Singh, K., Su, H.P., Klein, M. M., Stower, A. W., Saul, A. J., Long, C. and Garboczi, D. N. (2006). Plasmodium P25 and P28, essential proteins for survival of the malaria parasite in the mosquito is tile-like triangular prism (PDB-1Z27, 1Z1Y, 1Z3G).

    Nature (Struc. & Mol. Biol.) 13(1), 90-91.
Recent Peer Reviewed Journals/Books
  1. Yeshveer Singh, Ruby Sharma, Manasi Mishra, Praveen Kumar Verma# and Ajay K. Saxena# (2021). Crystal structure of ArOYE6 reveals a novel C-terminal fold and mechanistic insights into the distinct class III OYEs from pathogenic fungi.

    The FEBS Journal. 2022 Mar 21
  2. Arkita Bandhopadhyay and Ajay K. Saxena# (2021). Structural and ATPase activity analysis of nucleotide binding domain of Rv3870 enzyme of M. tuberculosis ESX-1 system.

    Int. J. Biol. Macromol 189: 879–889.
  3. Sumita Karan, Ankita Behl, Amin Sagar, Arkita Bandhopadhyay and Ajay K. Saxena# (2021). Structural studies on Mycobacterium tuberculosis HddA enzyme using small angle X-ray scattering and dynamics simulation techniques.

    Int. J. Biol. Macromol.171:28-36.
  4. S. Karan, B. Pratap, Shiv P. Yadav, FNU. Ashish & Ajay K. Saxena# (2020). Structural and functional characterization of M. tuberculosis sedoheptulose‑ 7‑phosphate isomerase, a critical enzyme involved in lipopolysaccharide biosynthetic pathway.

    Nature Sci. Rep. 10(1):20813.
  5. Sumita Karan, Bhanu pratap, Ashish and Ajay K. Saxena# (2019). Low-resolution SAXS and structural dynamics analysis on M. tuberculosis GmhB enzyme involved in GDP- heptose biosynthetic pathway.

    Int. J. Biol. Macromol. 136: 676–685.