Ph. D. (2005) Structure-Based Drug-Design, Department of Biophysics, All India Institute of Medical Sciences (AIIMS), New Delhi
Structure-Based Drug-Design,
Peptide Chemistry,
Synthetic Organic Chemistry,
Nanotechnology,
X-Ray Crystallography
Associate Professor (Chemistry) - School of Physical Sciences, JNU (Since January 2021)
Assistant Professor (Chemistry) - Swami Shraddhanand College, Delhi University, Delhi (2015 - 2021)
Senior Manager - Bioconcept Labs Pvt. Ltd, Manessar, Haryana (2013 - 2014)
Senior Scientist and Head - Peptide Therapeutics Research Laboratory, Onestream Research Centre (DSIR), Panacea Biotec Ltd, New Delhi (2008 - 2013)
Young Scientist (DST) - Institute of Nuclear Medicine and Allied Sciences (INMAS), DRDO, New Delhi (2006 - 2007)
Scientist B - Medicinal and Process Chemistry Division, Central Drug Research Institute (CDRI), Lucknow (2005 - 2006)
Young Scientist Award (2006), Department of Science and Technology (DST), New Delhi
Post Doctoral Fellowship (2007), Dartmouth College, Hanover, New Hampshire, United States
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- Synthesis of Specific SPECT-Radiopharmaceutical for Tumor Imaging Based on Methionine: 99mTc-DTPA-bis (methionine); Puja Hazari, Gauri Shukla, Vijay Goel, Krishna Chuttani, Nitin Kumar, Rajnish Sharma and Anil Mishra; Bioconjugate Chemistry 21(2)(2010) 229-239
- Effects of branched beta carbon dehydro residues on peptide conformation: Syntheses, crystal structures and molecular conformations of Cbz-DIle-Ala-DPhe-Ala-OCH3 and Cbz-DVal-Leu-DPhe-Leu-OCH3; V. K. Goel, R. K. Somvanshi, S. Dey and T. P. Singh, J. Peptide Res. 66(2) (2005) 68
- Design of peptides with a, b - dehydro residue: Crystal Structure and Molecular conformation of (i) Boc-Leu-DPhe-Leu-OCH3 and (ii) Boc-Ala-DPhe-Ala-OCH3.; V. K. Goel, S. Dey, R. K. Somvanshi and T. P. Singh; Structural Chemistry 16(4) (2005) 385-389
- Design of peptides with alpha-beta dehydro residue: Synthesis, Crystal Structure and Molecular conformation of Cbz-DVal-DPhe-Ala-OCH3. V. K. Goel, S. Dey and T. P. Singh, J. Mol. Struct. 738 (2005) 189-192
- Design rules for peptides with a, b - dehydro-residues: Synthesis of a model peptide Boc-Ile-DAla-OCH3 and its crystal structures obtained from two different solvents.; S. Dey, R. Vijayaraghavan, V. K. Goel, S. Kumar, P. Kumar, and T. P. Singh; J. Mol. Struct. 737 (2005) 109-116.
- Design of peptides with alpha-beta dehydro residue: Crystal Structure and Molecular conformation of Boc Phe-DPhe-Ile-OCH3 R, Vijayaraghavan, V. K. Goel, S. Dey, and T. P. Singh; Structural Chem. 16(4) (2005) 445-452
- Design of peptides with alpha-beta dehydro residue: Crystal Structure and Molecular conformation of Boc-Ala-DPhe-DPhe-Phe-OCH3 R. K. Somvanshi, V. K. Goel, S. Dey and T. P. Singh; J. Chem. Cryst. 35 (2005) 761-768
- Crystallographic analysis of 9-(3-methylbut-2-enyloxyfurano) [3,2-g] benzopyran-2-one; Rajnikant, Dinesh, A. S. Shawl, T. P. Singh, V. K. Goel and Bandhan Sharma; Journal of Chemical Crystallography, 35 (2005) 913-916
- Design of peptides with a, b - dehydro-residues: Crystal Structure of Boc-Leu-DPhe-Ile-OCH3, C27H43N3O7; V. K. Goel, M. Guha, A. P. Baxla, S. Dey and T. P. Singh; J. Mol. Struct. 658 (2003) 135-141.
- Kanika D, Chandra A, Kumar V, Othayoth J, Rathi B and Goel VK. Identification of Novel Peptide Inhibitors of Plasmodium falciparum Dihydrofolate Reductase (PfDHFR): Molecular docking and MD Simulation Studies, Journal of Biomolecular Structure and Dynamics, 2024, DOI:10.1080/07391102.2024.2335288
- Colaco V, Goswami N, Goel VK, et al. In silico and structure-based evaluation of deleterious mutations identified in human Chk1, Chk2, and Wee1 protein kinase. J Cell Biochem. 2024;125(1):89-99. doi:10.1002/JCB.30508
- Shukla R, Chandra A, Kumar A, et al. Repurposing of drugs against methyltransferase as potential Zika virus therapies. Scientific Reports 2023 13:1. 2023;13(1):1-15. doi:10.1038/s41598-023-33341-6
- Abdullahi M, Uzairu A, Shallangwa GA, et al. Molecular modelling studies of substituted indole derivatives as novel influenza a virus inhibitors. J Biomol Struct Dyn. Published online 2023. doi:10.1080/07391102.2023.2280735
- Jee B, Sharma PP, Goel VK, Kumar S, Singh Y, Rathi B. Natural Metabolite Ursolic Acid as an Inhibitor of Dormancy Regulator DosR of Mycobacterium tuberculosis : Evidence from Molecular Docking, Molecular Dynamics Simulation and Free Energy Analysis . Curr Comput Aided Drug Des. 2023;19(6). doi:10.2174/1573409919666230201100543
- Kherwal M, Gupta A, Jacob M, et al. Recent advances in self-assembled cyclic peptide-based smart nano-structures. Applied Chemical Engineering. 2023;6(1). doi:10.24294/ace.v6i1.1989
- Sharma R, Borah SJ, Bhawna, et al. Functionalized Peptide-Based Nanoparticles for Targeted Cancer Nanotherapeutics: A State-of-the-Art Review. ACS Omega. 2022;7(41). doi:10.1021/acsomega.2c03974
- Abdullahi M, Uzairu A, Shallangwa GA, et al. In-silico molecular modelling studies of some camphor imine based compounds as anti-influenza A (H1N1) pdm09 virus agents. J Biomol Struct Dyn. Published online 2024. doi:10.1080/07391102.2023.2209654
- Sharma PP, Bhardwaj S, Sethi A, et al. Chitosan based architectures as biomedical carriers. Carbohydr Res. 2022;522. doi:10.1016/j.carres.2022.108703
- Sharma PP, Bansal M, Sethi A, et al. Computational methods directed towards drug repurposing for COVID-19: advantages and limitations. RSC Adv. 2021;11(57):36181-36198. doi:10.1039/D1RA05320E
"TUMOR NECROSIS FACTOR ALPHA INHIBITING PEPTIDES AND USES THEREOF" International Publication Number: WO 2010/058419 A1; Assignee: Panacea Biotec Pvt Ltd.; Inventors: Rajesh Jain, V. K. VInayak, Sudhanand Prasad, Shweta Dubey, Vijay Goel and Rahul Jain; US Patent App. 13/130,267